Indian Scientists Discover How Serotonin Helps Brain Cells Cope with Stress

Prelims level : Serotonin Mains level : Science & Technology
No Set Found with this ID

Why in News?

  • Indian scientists have discovered that serotonin boosts energy production in brain cells and helps them survive under stress. This new knowledge can potentially be used to develop anti-stress drugs in

Role of Serotonin:

  • Serotonin is a chemical that relays information from one part of the brain to another and is known to play a key role in a number of functions ranging from sleep to social
  • The study by scientists at the Mumbai-based Tata Institute of Fundamental Research (TIFR) has found that the neurotransmitter boosts the number of mitochondria in brain cells.
  • Mitochondria in brain cells generate energy to carry out cellular functions and play a role in survival of brain cells under
  • In addition, serotonin also increases production of energy by
  • This role of serotonin in regulating neuronal energetics was not known till

Benefits of Serotonin:

  • Serotonin reduces toxic reactive oxygen species in neurons, boosts anti-oxidant enzymes and buffers neurons from the damaging effects of cellular
  • The study has uncovered an unprecedented role of serotonin in energy production in neurons, directly impacting how neurons handle
  • It has also identified novel therapeutic targets for the treatment of neurodegenerative and psychiatric

Energy boosting function:

  • Researchers have also found out the mechanism through which serotonin carries out its energy boosting
  • It has emerged that generation of new mitochondria in neurons by serotonin is accompanied by increased cellular respiration and energy chemical
  • These effects of serotonin involve the serotonin2A receptor and master regulators of mitochondrial generation – SIRT1 and PGC-1a.
Share Socially