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GS 3: Science & Technology – Awareness In The Fields Of It, Space, Computers, Robotics, Nano-Technology, Bio-Technology

Why in News?

African Nation, Malawi will be undertaking large scale pilot tests for the world’s most advanced experimental malaria vaccine in a bid to prevent the disease.


  • The vaccine has been recommended by WHO for pilot introduction in selected areas of 3 African countries- Ghana, Kenya and Malawi.
  • RTS,S, known by its trade name Mosquirix, uses antibodies to target proteins presented by sporozoites (such as the circumsporozoite protein of falciparum).
  • To enhance the immune system and help prevent the parasite from infecting the liver.
  • Mosquirix is also engineered using a hepatitis B viral protein and a chemical adjuvant to further boost the immune response for enhanced effectiveness.


  • It is caused by the infectious Plasmodium.
  • It is spreaded by female Anopheles Mosquitoes deposit parasite sporozoites into the skin of a human host.
  • Malaria is a leading cause of human morbidity and mortality.
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