Recombinant ELISA Kits

Why in News?

  • Union Minister of Agriculture & Farmers released recombinant Enzyme-linked immune sorbent assay (ELISA) kits: one for Glanders and other for Equine Infectious Anaemia.
  • Both these diseases are notifiable diseases in India and require special diagnosis for control and eradication in the country.


  • National Research Centre on Equines (NRCE) has been able to develop a recombinant Hcp1 antigen ELISA as an alternate to complement-fixation test (CFT). The ELISA has been duly validated in India and the OIE (World Organisation for Animal Health) Reference Laboratory, Germany.

Glanders Disease:

  • Glanders is a fatal infectious and notifiable disease of equines including horses, donkeys and mules. The disease is caused by a bacterium known as Burkholderia mallei and has zoonotic potential. The organism is also considered as potential bio-weapon and categorized under ‘Tier 1 Select Agent’.

Equine Infectious Anaemia(EIA):

  • Equine infectious anaemia (EIA) is a chronic, debilitating and persistent infectious disease of equines caused by a retrovirus. It is an OIE (Office International des Epizooties) notifiable disease. NRCE has also developed recombinant p26 protein-based ELISA as an alternative to Coggin’s test. This technology will provide sustainable and homogeneous source of antigen and harmonized protocol to ensure regular surveillance of EIA.
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